pentobarbital will decrease the extent or effect of lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with powerful CYP3A4 inducers can lead to reduced serum concentrations and loss of antimalarial efficacy

pentobarbital will reduce the extent or result of phenytoin by affecting hepatic enzyme CYP2C9/10 metabolism. Use Warning/Keep an eye on.

pentobarbital will minimize the extent or effect of sulfamethoxazole by affecting hepatic enzyme CYP2C9/ten metabolism. Slight/Importance Unidentified.

The go drew Substantially unwanted awareness to Valeant, presently embroiled in federal probes following steep rate hikes to 2 heart drugs—one particular by a lot more than five hundred %. But the furor encompassing Seconal’s rate improve elevated another difficulty, too.

pentobarbital will lower the extent or effect of tadalafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Stay clear of mixture in pulmonary HTN individuals. For clients with ED, observe response to tadalafil cautiously as a consequence of potential for diminished performance.

pentobarbital will minimize the extent or impact of bosentan by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Mysterious.

Therapy needs to be administered with warning, if whatsoever, to patients that are mentally depressed, have suicidal tendencies, or background of drug abuse

pentobarbital will decrease the extent or impact of alfuzosin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Mysterious.

pentobarbital will decrease the extent or effect of celecoxib by impacting hepatic enzyme CYP2C9/10 metabolism. Slight/Importance Unfamiliar.

pentobarbital will lessen the level or impact of etravirine by impacting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Keep an eye on.

pentobarbital will more info enhance the degree or outcome of clopidogrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.

pentobarbital will reduce the extent or impact of bosentan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unknown.

buprenorphine transdermal and pentobarbital both boost sedation. Avoid or Use Alternate Drug. Limit use to sufferers for whom different treatment alternatives are inadequate

This drug may perhaps improve the metabolism of estradiol when administered concurrently; individuals on oral contraceptives have become Expecting when concurrently treated with antiepileptic drugs; advise an alternate contraceptive approach to women getting this drug